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With practical pointers from regional professionals, we've created a list of appealing biotech startups in Switzerland. 2019 Zurich, Araris Biotech is a spin-off from the Swiss Paul Scherrer Institute and the ETH Zurich. The company deals with antibody-drug conjugates (ADCs), a type of drug where a poisonous agent is attached to an antibody with a so-called linker.

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For instance, the antibody part of the drug should typically go through expensive and time-intensive engineering, slowing the ADC's development. To resolve this obstacle, Araris Biotech has established a linker platform that permits the accessory of any harmful representative to off-the-shelf antibodies, lowering the need for prior antibody engineering. In late 2020, the business raised 13.

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2M) in a seed round to boost the preclinical and clinical development of its lead ADCs. 2017 Zurich, CDR-Life is developing antibody pieces to treat cancer and retinal diseases. The business's antibodies target tumor-specific proteins inside cancer cells and assist a client's own T cells to attack and eliminate these cells.

The startup just recently entered into a contract with the German pharma giant Boehringer Ingelheim to co-develop treatments based upon antibody pieces for the irreversible retinal disease geographic atrophy, which occurs in clients with age-related macular degeneration. CDR-Life will be qualified to get up to 434M (CHF 474. 5M) in upfront and milestone payments, research study financing, along with royalties on prospective sales.

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The regenerative medicine startup develops skin grafts to deal with serious burns. Big and deep burns can reach the dermis the lower layer of skin tissue which can result in unpleasant and disfiguring scarring. Presently, burns of this intensity are dealt with by taking a skin graft from another part of the client's body, but these often contain extremely little tissue from the dermis layer and still trigger scarring.

The business then develops a tailored skin graft containing both the epidermis and dermis layers.  Hayas Clothing  has finished a phase I medical trial in pediatric patients and is now being checked in stage II in adults and children. In July 2020, Cutiss raised 19M in a Series B financing round to support its stage II scientific trial and scale-up manufacturing in Switzerland.